Dr. Melillo’s message focuses on how regular use of Tylenol PM can damage internal organs. He explains that the combination of acetaminophen and diphenhydramine increases the risk of long-term damage, especially if used incorrectly.
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Paracetamol and Liver Damage
Paracetamol is generally safe in the right dosage. However, more than 4,000 milligrams per day can cause acute liver failure. People with liver disease or those who drink alcohol face an even greater risk.
In the United States, acetaminophen is one of the leading causes of liver failure. Many people accidentally exceed the safe dose by taking multiple products containing it.
Sick woman suffering from pain in the bathroom and illustration of an unhealthy liver. Hepatitis disease
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Diphenhydramine and its effects
Diphenhydramine helps with sleep and allergies, but long-term use can cause confusion, dizziness, and memory problems, especially in the elderly. Some research also suggests that it may affect kidney function.
